Ahmed Al-Harrasi

Multistep synthesis of novel indole–benzimidazole hydrazone hybrids as xanthine oxidase inhibitors: In-Vitro evaluation, molecular docking, MD simulations and DFT studies

This work reports the synthesis of a focused library of indole-benzimidazole hydrazone hybrids ( 17 - 35 ) via a multistep procedure involving thiolation, hydrazination, and Schiff base condensation. The final structures were confirmed using 1 H-NMR, 13 C-NMR, and FT-IR spectrosc...