Adura Emmanuel Adebunmi

Oxidative Stress Burden in Paediatric Sickle Cell Anaemia: Effects of Hydroxyurea Therapy, Disease Severity, and Socioeconomic Factors

Background: Oxidative stress plays a central role in the pathophysiology of sickle cell anaemia (SCA), contributing to haemolysis, endothelial dysfunction, and disease complications.Hydroxyurea (HU), the main disease-modifying therapy for SCA, may influence oxidative balance; how...