Adrian V. S. Hill

Preclinical Evaluation of the SMNP-Adjuvanted R21 Malaria Vaccine Across Multiple Mouse Strains

Background: Adjuvants can enhance the immunogenicity of virus-like particle (VLP) vaccines. VLP-based malaria vaccines (RTS,S and R21) have demonstrated the potential of this approach and have now been deployed in many countries. However, the efficacy of these vaccines decays ove...