Adam Turnbull

Stage-dependent associations of glial fibrillary acidic protein and chitinase-3-like protein 1 with white matter network integrity in Alzheimer's disease

Background Astrocytes become reactive in Alzheimer's disease (AD), and fluid markers of this response, including glial fibrillary acidic protein (GFAP) and chitinase-3-like protein 1 (YKL-40), increase across the AD continuum. However, it remains unclear whether astrocytic biomar...