Adam Duong

Vicinal Halothiolcarbonates as Pseudo-Ambident Electrophiles: Carbamate Synthesis, Unified Thiol Reactivity, and Architecture-Dependent Antibacterial Activity of Ciprofloxacin Glycoconjugates

Abstract Vicinal bis-electrophilic halothiolcarbonates (vic-HTCs) are introduced as a platform for the chemoselective synthesis of carbohydrate carbamates under mild conditions. Their aminolysis accommodates a broad range of nucleophiles, including complex bioactive amines, provi...