Abhijit Gaikwad

Design, Synthesis and Biological Evaluation of Thiazole Derivatives: An Integrated Molecular Docking and Density Functional Theory Investigation

A series of nine thiazole-hydrazone hybrids (D1-D9) was prepared in two steps: 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde was condensed with thiosemicarbazide, and the resulting thiosemicarbazone was cyclized with substituted phenacyl bromides. The products were characteriz...