Abdulla Abu-Salah

Comparative proteomic analysis of environmental and genetic models of Parkinson’s disease highlights the role of purine metabolism

Parkinson’s Disease (PD) is the second most common neurodegenerative disease, with many cases attributed to environmental exposures. Paraquat (PQ), is a pesticide and neurotoxicant strongly associated with increased PD risk. PQ is a weak inhibitor of complex I of the electron tra...