Abdelwahap Elghezewi

Alpha-Gal Syndrome and the Gastrointestinal Tract: Epidemiology, Clinical Phenotype, Diagnosis, Management, and the Case for a Public Health Response

Alpha-gal syndrome (AGS) is a tick-induced, IgE-mediated hypersensitivity to the oligosaccharide galactose-α-1,3-galactose (α-gal), which is expressed on glycoproteins and glycolipids of non-primate mammals but absent in humans. Gastrointestinal (GI) symptoms dominate the clinica...