Andrea Martirena

Pancreatic ductal adenocarcinoma with atypical biliary obstruction secondary to tension pneumobilia: a case report

Most patients diagnosed with pancreatic cancer present with constitutional syndrome, abdominal pain, and/or jaundice. Jaundice is typically due to tumor-induced biliary obstruction. However, as we will illustrate in our clinical case, rare obstructive mechanisms can sometimes occ...

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...