Researchers searched several medical and African research databases for peer-reviewed studies available through March 15, 2024. They combined prevalence estimates using a random-effects statistical model and examined differences by diagnostic method and geographic region.

The pooled estimate was 34%, with a 95% confidence interval of 24% to 44%. Estimates were higher when diagnosis was based only on clinical examination than when cases were confirmed by laboratory testing, and West Africa had the highest regional estimate in the analysis. These findings describe patterns across the included studies; they do not establish the prevalence in every Sub-Saharan African country or community.